https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
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Rotary movement of DNA rotors on nanopores. Best row: Uncooked movie from the Cy5 channel of each and every rotor. Center row: corresponding single-particle localization benefits of each finishes in the DNA rotors. The position of the current body is marked as orange and blue dots, along with the trajectory of the 10 frames ahead of the current body is revealed as reliable strains.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
Like a individual, I contain the biblical assignment to discover and use almost everything in generation for the benefit of my neighbour. I usually do not working experience any conflict among faith and science. Quite the opposite, my religion stimulates me to carry out science, being open-minded on the earth.’
2007, initial genuine-time detection of strand exchange in homologous recombination by RecA; discovery of a reduced persistence length of ends of microtubules; and resolved the system of biosensing with carbon nanotubes
2015, discovery that condensin is really a remarkably adaptable protein construction; and 1st detection of DNA knots using nanopores
From the decades pursuing these discoveries, my exploration passions shifted to biophysics and nanobiology, and I turned fewer involved with the development of nanotube electronics. The focus of numerous scientists in the field also shifted to graphene (where, funnily more than enough, the 1st graphene ribbons have been described as ‘nanotubes which have been Slice open along their size’) right after the invention of The 2-dimensional content in 2004.
We condition micro organism into varieties that deviate from their normal phenotype. Especially, I will show our power to form Dwell E. coli germs into novel styles for instance rectangles, squares, triangles and circles.
2000, discovery that nanotubes can have incredible big recent densities; fixed the controversial concern of Digital transportation through DNA molecules by measurements of insulating conduct at The only molecule amount; and demonstration of an AFM approach for solitary-molecule manipulation of nanotubes
In 1993, as being a young and eager associate professor at Delft University of Technology, I had initially focused the investigate efforts of my group on measuring the electrical conductance ceesdekker of an individual conducting-polymer molecule. In just two years, we experienced established a tool where one wire of a phthalocyaninepolysiloxane polymer was connected in between two closely spaced metallic nanoelectrodes.
But carbon nanotubes have remained a exploration matter of significant curiosity to several. Certainly, the outlook on utilizing carbon nanotubes to build practical equipment, in parts for instance radio-frequency electronics, digital electronics and flexible electronics, continues to be shiny.
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Cees Dekker is Distinguished College Professor at TU Delft. Qualified like a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes in the nineteen nineties. Considering that 2000, he moved to single-molecule biophysics and nanobiology. His present analysis concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, especially SMC motor protein; and (iii) building a dwelling synthetic mobile from lifeless molecules. Dekker is surely an elected member of your KNAW and fellow on the APS and the IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style and design in 2005. (nl)